ANALISIS KADAR PROTEIN URIN DAN ALBUMIN SERUM PADA PENYAKIT GAGAL GINJAL KRONIK

Abstract

Introduction: Chronic Kidney Disease (CKD) is a progressive and irreversible disorder of kidney function. urine protein is an important marker of gradual renal damage and is independently associated with the development of chronic renal failure and the incidence of cerebrovascular disease. Increased urine protein levels and decreased serum albumin levels are the main signs in CKD patients. The global prevalence of chronic kidney disease is estimated at 9.1%, and was ranked the 12th cause of death in 2017.  Objective: This study aims to analyze the correlation between urine protein levels and albumin levels in CKD patients. Method: The research design was cross-sectional analytic using secondary data of 80 medical record of patients diagnosed with CKD who underwent treatment at the RSUD Pasar Rebo Jakarta Timur  during the January to December 2023. Data analysis using Spearman analysis. Results: The results of this study showed that 80 patient medical record data had abnormal levels of urine protein and albumin levels. The results of the Spearman correlation test showed that there was a significant correlation between urine protein levels and serum albumin levels in CKD patients (p < 0.00). This indicates that increasing urine protein levels are associated with decreasing serum albumin levels. Conclusion: There is a negative correlation between urine protein levels and albumin levels in CKD patients. The higher the urine protein level, the lower the serum albumin level.